Article
Rescue of Drosophila labial null mutant by the chicken ortholog Hoxb-1 demonstrates that the function of Hox genes is phylogenetically conserved.
Genes & development - 15 Jan 1996
Lutz B, Lu H C, Eichele G, Miller D, Kaufman T C
Abstract excerpt
Hox complexes are important players in the establishment of the body plan of invertebrates and vertebrates. Sequence comparison demonstrates a remarkable phylogenetic conservation of key structural features of Hox genes. The correlation between the physical order of genes along the chromosomes an...
Topics
- Amino Acid Sequence
- Animals
- Animals, Genetically Modified
- Base Sequence
- Chickens
- Conserved Sequence
- DNA Primers
- Drosophila
- Drosophila Proteins
- Gene Deletion
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Homeodomain Proteins
- Insect Hormones
- Molecular Sequence Data
- Phenotype
- Sequence Homology, Amino Acid