Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

1 Jan 1996

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related Molecular Pathways
Share to Microtubule and mitosis dynamics

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 8564846
DOI: 10.1038/nm0196-72

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosisPMID 8564846Read ↗

p53 acetylation enhances Taxol-induced apoptosis in human cancer cellsSemantic proximity Read ↗

Taxol-induced cell cycle arrest and apoptosis: dose–response relationship in lung cancer cells of different wild-type p53 status and under isogenic conditionSemantic proximity Read ↗

Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell deathSemantic proximity Read ↗

Inactivation of p53 in a Human Ovarian Cancer Cell Line Increases the Sensitivity to Paclitaxel by Inducing G2/M Arrest and ApoptosisSemantic proximity Read ↗

Human T-cell leukemia virus I tax protein sensitizes p53-mutant cells to DNA damage.Semantic proximity Read ↗

Mechanisms of cancer cell death induction by paclitaxel: an updated reviewSemantic proximity Read ↗

Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.Semantic proximity Read ↗

Acquisition of taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cellsSemantic proximity Read ↗

Protection of p53 wild type cells from taxol by nutlin-3 in the combined lung cancer treatment.Semantic proximity Read ↗

Normal p53 status and function despite the development of drug resistance in human breast cancer cells.Semantic proximity Read ↗

Loss of p21 disrupts p14ARF-induced G1 cell cycle arrest but augments p14ARF-induced apoptosis in human carcinoma cellsSemantic proximity Read ↗

Low Concentrations of Taxol Cause Mitotic Delay Followed by Premature Dissociation of p55CDC from Mad2 and BubR1 and Abrogation of the Spindle checkpoint, Leading to AneuploidySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.