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Article

Expression of the exon 1A-containing PMP22 transcript is altered in the trembler mouse.

Neuroscience letters - 6 Oct 1995

Garbay B, Boiron-Sargueil F, Cassagne C

Abstract excerpt

The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP22) gene which results in an abnormal myelination of its peripheral nervous system. The recent identification of two different PMP22 mRNA differing in their 5' non-translated region led us to monitor their respective levels of expression in the trembler peripheral nervous system (PNS) during the myelination...

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Source

Identifiers

PMID: 8552310
DOI: 10.1016/0304-3940(95)12008-r

Genes

PMP22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of the exon 1A-containing PMP22 transcript is altered in the trembler mouse.PMID 8552310Read ↗

Expression of the PMP-22 gene in Trembler mutant mice: comparison with the other myelin protein genes.Semantic proximity Read ↗

Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves.Semantic proximity Read ↗

Peripheral myelin protein 22: facts and hypotheses.Semantic proximity Read ↗

Elevated expression of messenger RNA for peripheral myelin protein 22 in biopsied peripheral nerves of patients with Charcot‐Marie‐Tooth disease type 1ASemantic proximity Read ↗

Identification of a positive regulatory element in the myelin-specific promoter of the PMP22 gene.Semantic proximity Read ↗

Trembler mouse carries a point mutation in a myelin gene.Semantic proximity Read ↗

A leucine-to-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse.Semantic proximity Read ↗

Widespread expression of the peripheral myelin protein‐22 gene (<i>pmp</i>22) in neural and non‐neural tissues during murine developmentSemantic proximity Read ↗

Correlation between varying levels of PMP22 expression and the degree of demyelination and reduction in nerve conduction velocity in transgenic miceSemantic proximity Read ↗

Development of early postnatal peripheral nerve abnormalities in Trembler‐J and PMP22 transgenic miceSemantic proximity Read ↗

Studies on the effects of altered PMP22 expression during myelination in vitroSemantic proximity Read ↗

Induced myelination and demyelination in a conditional mouse model of Charcot-Marie-Tooth disease type 1A.Semantic proximity Read ↗

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