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Article

Effect of polymorphism in the Drosophila regulatory gene Ultrabithorax on homeotic stability.

Science (New York, N.Y.) - 12 Jan 1996

Gibson G, Hogness D S

Abstract excerpt

Development is buffered against unpredictable environmental and genetic effects. Here, a molecular genetic analysis of one type of developmental homeostasis, the establishment of thoracic segmental identity under the control of the Ultrabithorax (Ubx) gene in Drosophila melanogaster, is presented. Flies were artificially selected for differential sensitivity to the induction of bithorax phenocopies by ether...

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Identifiers

PMID: 8539619
DOI: 10.1126/science.271.5246.200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Effect of polymorphism in the Drosophila regulatory gene Ultrabithorax on homeotic stability.PMID 8539619Read ↗

Evolution of developmental genes: molecular microevolution of enhancer sequences at the Ubx locus in Drosophila and its impact on developmental phenotypes.Semantic proximity Read ↗

Is function of the Drosophila homeotic gene Ultrabithorax canalized?Semantic proximity Read ↗

Regulation of Ubx expression by epigenetic enhancer silencing in response to Ubx levels and genetic variation.Semantic proximity Read ↗

Polycomb-dependent Ultrabithorax Hox gene silencing induced by high Ultrabithorax levels in Drosophila.Semantic proximity Read ↗

The role of Ultrabithorax in the patterning of adult thoracic muscles in Drosophila melanogaster.Semantic proximity Read ↗

The function and regulation of Ultrabithorax in the legs of Drosophila melanogaster.Semantic proximity Read ↗

Function of an Ultrabithorax minigene in imaginal cells.Semantic proximity Read ↗

Redundant control of Ultrabithorax by zeste involves functional levels of zeste protein binding at the Ultrabithorax promoter.Semantic proximity Read ↗

The hangover gene defines a stress pathway required for ethanol tolerance development.Semantic proximity Read ↗

Positive and negative cis-regulatory elements in the bithoraxoid region of the Drosophila Ultrabithorax gene.Semantic proximity Read ↗

Trans regulation in the Ultrabithorax gene of Drosophila: alterations in the promoter enhance transvection.Semantic proximity Read ↗

Functional dissection of Ultrabithorax proteins in D. melanogaster.Semantic proximity Read ↗

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