Article
Positive and negative cis-regulatory elements in the bithoraxoid region of the Drosophila Ultrabithorax gene.
Molecular & general genetics : MGG - 1 Aug 1992
Castelli-Gair J E, Capdevila M P, Micol J L, García-Bellido A
Abstract excerpt
The Ultrabithorax (Ubx) gene is required during embryogenesis and larval development to specify the third thoracic and first abdominal segments of Drosophila melanogaster. Mutations in the bithoraxoid (bxd) region, a 40 kb DNA stretch upstream of the Ubx promoter, affect cis-regulatory elements responsible for the ectodermal expression of the Ubx gene in the posterior compartment of the third thoracic segment and...
Topics
- Alleles
- Animals
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation
- Genes, Homeobox
- Homeodomain Proteins
- Mutation
- Regulatory Sequences, Nucleic Acid