Article
Evidence for genetic regulation of susceptibility to toxoplasmic encephalitis in AIDS patients.
The Journal of infectious diseases - 1 Jan 1996
Suzuki Y, Wong S Y, Grumet F C, Fessel J, Montoya J G, Zolopa A R, Portmore A, Schumacher-Perdreau F, Schrappe M, Köppen S, Ruf B, Brown B W, Remington J S
Abstract excerpt
The frequency of HLA-DQ antigens in AIDS patients with toxoplasmic encephalitis (TE) were examined. HLA-DQ3 was significantly more frequent in white North American AIDS patients with TE (85.0%) than in the general white population (51.8%; P = .007, corrected P = .028) or randomly selected control AIDS patients who had not developed TE (40.0%; P = .016). In contrast, the frequency of HLA-DQ1 was lower in TE...
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