Article
Spontaneous mutation as a risk factor.
Experimental and clinical immunogenetics - 1 Jan 1995
Crow J F
Abstract excerpt
From various estimates of the mutation rate per nucleotide per generation, centering around 1-2 x 10(-8) and the number of nucleotide pairs, 3 x 10(9) per genome, the number of new mutations in a human zygote is very large, in the order of 100. The mutation rate is an order of magnitude higher in...
Topics
- Age Factors
- Animals
- DNA
- Drosophila melanogaster
- Female
- Fertility
- Genetic Diseases, Inborn
- Humans
- Male
- Mutation
- Risk Factors
- Selection, Genetic
- Sex Characteristics