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Article

Population dynamics of a meiotic/mitotic expansion model for the fragile X syndrome.

American journal of human genetics - 1 Dec 1995

Ashley A E, Sherman S L

Abstract excerpt

A model to explain the mutational process and population dynamics of the fragile X syndrome is presented. The mutational mechanism was assumed to be a multipathway, multistep process. Expansion of CGG repeats was based on an underlying biological process and was assumed to occur at two time points: meiosis and early embryonic development (mitosis). Meiotic expansion was assumed to occur equally in oogenesis and...

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Identifiers

PMID: 8533772
PMCID: PMC1801421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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