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Organization of the Gene Encoding the Human Endothelin-converting Enzyme (ECE-1)

1 Dec 1995

Abstract excerpt

The two human endothelin-converting enzyme (ECE-1) isoforms, which differ by their N-terminal region, are encoded by a single gene. The gene is composed of 19 exons that span more than 68 kilobases and has been mapped to the 1p36 band of the human genome. The two isoform mRNAs display different tissue distributions. Their precursors are transcribed from two distinct start sites, upstream from exon 1 and exon 3,...

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PMID: 8530372
DOI: 10.1074/jbc.270.50.29794

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