Article
Determination of oestrogen responsiveness of breast cancer by competitive reverse transcription-polymerase chain reaction.
British journal of cancer - 1 Dec 1995
Carr M, May F E, Lennard T W, Westley B R
Abstract excerpt
Competitive polymerase chain reaction assays have been developed for the quantitation of oestrogen receptor mRNA and two oestrogen-regulated mRNAs (progesterone receptor and pNR-2/pS2) in breast cancer cells. These assays are more sensitive than traditional hybridisation techniques, do not require the use of radioisotopes, measure absolute amounts of messenger RNAs and can be used to measure the expression of...
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