Article
Increased expression of heat shock protein 65 coincides with a population of infiltrating T lymphocytes in atherosclerotic lesions of rabbits specifically responding to heat shock protein 65.
The Journal of clinical investigation - 1 Jun 1993
Xu Q, Kleindienst R, Waitz W, Dietrich H, Wick G
Abstract excerpt
We have shown previously that atherosclerotic lesions can be induced in normocholesterolemic rabbits by immunization with mycobacterial heat shock protein 65 (hsp65), which has a high degree of sequence homology with mammalian hsp60. To investigate a possible relationship between hsp60 expression...
Topics
- Animals
- Antibody Formation
- Aorta
- Arteriosclerosis
- Bacterial Proteins
- Cell Division
- Cell Line
- Cell Movement
- Chaperonin 60
- Chaperonins
- Cholesterol
- Endothelium, Vascular