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Article

Multiple pathways of reversion in viroids for conservation of structural elements.

The EMBO journal - 1 May 1993

Qu F, Heinrich C, Loss P, Steger G, Tien P, Riesner D

Abstract excerpt

From site-directed mutagenesis of potato spindle tuber viroid (PSTVd) it had been concluded earlier that the formation of a thermodynamically metastable structure containing hairpin II (HP II) is critical for infectivity. In order to differentiate between structural and sequence effects, in the present work base pairs in HP II were exchanged by site-directed double mutations without significant alterations in the...

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Identifiers

PMID: 8491201
DOI: 10.1002/j.1460-2075.1993.tb05861.x
PMCID: PMC413434

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Multiple pathways of reversion in viroids for conservation of structural elements.PMID 8491201Read ↗

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Biased Pol II fidelity contributes to conservation of functional domains in the Potato spindle tuber viroid genome.Semantic proximity Read ↗

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