Article
Genomic organization of the human HBNF gene and characterization of an HBNF variant protein as a splice mutant.
Biochemical and biophysical research communications - 30 Apr 1993
Kretschmer P J, Fairhurst J L, Hulmes J D, Popjes M L, Böhlen P, Kovesdi I
Abstract excerpt
The organization of the human heparin-binding neurite outgrowth promoting factor (HBNF) gene is presented. Based on Southern analysis and the isolation of genomic DNA clones from a lambda phage library, the minimum size of the gene is 42 kb. Sequences comprising the HBNF mRNA are contained in five exons which account for the 1650 nt mRNA size observed by northern analysis. From the structure of the gene it is...
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