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Article

Glutathione S-transferase mu polymorphism does not explain variation in nitroglycerin responsiveness.

Clinical pharmacology and therapeutics - 1 Apr 1993

Haefeli W E, Srivastava N, Kelsey K T, Wiencke J K, Hoffman B B, Blaschke T F

Abstract excerpt

OBJECTIVE: To determine whether the considerable interindividual variability in nitroglycerin-induced venodilation in humans is related to the polymorphic expression of the mu class of glutathione S-transferase (GST mu). Recently vascular glutathione S-transferase (EC 2.5.1.18) of the mu-class (GST mu), a polymorphic group of enzymes present in only about 60% of the population, have been identified and shown in...

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Identifiers

PMID: 8477563
DOI: 10.1038/clpt.1993.52

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glutathione S-transferase mu polymorphism does not explain variation in nitroglycerin responsiveness.PMID 8477563Read ↗

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Correlation between trans-stilbene oxide-glutathione conjugation activity and the deletion mutation in the glutathione S-transferase class mu gene detected by polymerase chain reaction.Semantic proximity Read ↗

Polymorphic distribution of glutathione transferase activity with methyl chloride in human blood.Semantic proximity Read ↗

Glutathione transferase activity in human vessels and in cultured arterial smooth muscle cells.Semantic proximity Read ↗

Variation in the expression of Mu-class glutathione S-transferase isoenzymes from human skeletal muscle. Evidence for the existence of heterodimers.Semantic proximity Read ↗

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