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Article

Incomplete development of human spermatozoa is associated with increased creatine phosphokinase concentration and abnormal head morphology

1 Mar 1993

Abstract excerpt

Our previous creatine phosphokinase (CK) activity studies in human sperm revealed differences among men and among sperm populations within the same specimen. Samples with low sperm concentrations, high incidence of abnormal sperm morphology, and diminished fertility had higher per sperm CK activity. In the present work, we demonstrated, with 14C-FDNB covalent CK active site modification and with direct CK...

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PMID: 8471251
DOI: 10.1002/mrd.1080340309

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