Article
Human sperm anatomy: ultrastructural localization of 1α,25‐dihydroxyvitamin D3 receptor and its possible role in the human male gamete
30 Oct 2008
Abstract excerpt
Previous studies have suggested that 1alpha,25-dihydroxyvitamin D(3)[1,25(OH)(2)D(3)] has a role in reproductive function. Gonadal insufficiencies were observed as a result of 1,25(OH)(2)D(3) deficiency and in 1,25(OH)(2)D(3) receptor (VDR) null mutant mice. To study human sperm anatomy at the molecular level, we first evaluated the ultrastructural localization of VDR by immunogold electron microscopy using a...
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