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Article

[Clinical study and genetic 3q28 locus linkage in 2 Swiss families with Kjer dominant optic atrophy (OPA1)].

Klinische Monatsblatter fur Augenheilkunde - 1 May 1998

Lefèvre A, Hiroz C, Zografos L, Schorderet D F, Munier F L

Abstract excerpt

METHODS: We examined 20 patients from 2 unrelated Swiss families to describe their clinical phenotype. In addition, a linkage analysis was performed in an attempt to confirm the reported genetic homogeneity of this condition as well as to refine its genomic localization. RESULTS: Two point analysis provided a cumulative LOD-score of 3.03 with marker D3S 2305. The absence of recombination precluded further...

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Identifiers

PMID: 9677562

Genes

OPA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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[Clinical study and genetic 3q28 locus linkage in 2 Swiss families with Kjer dominant optic atrophy (OPA1)].PMID 9677562Read ↗

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Clinical and genetic analysis of a family affected with dominant optic atrophy (OPA1)Semantic proximity Read ↗

Mapping of a gene for autosomal dominant juvenile-onset open-angle glaucoma to chromosome Iq.Semantic proximity Read ↗

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