Article
Differential effects of bryostatin 1 on human non-Hodgkin's B-lymphoma cell lines.
Leukemia research - 1 Jan 1993
Mohammad R M, al-Katib A, Pettit G R, Sensenbrenner L L
Abstract excerpt
Bryostatin 1 (Bryo1), a macrocyclic lactone and a protein kinase C activator, is extracted and purified from the marine bryozoan Bugula neritina. In this study we describe its effect on morphology, surface immunophenotype, acid phosphatase (AcP), tartrate-resistant acid phosphatase (TRAP), proliferation and cell cycle of non-Hodgkin's B-lymphoma cell lines representing four differentiation stages. Except for the...
Topics
- Acid Phosphatase
- Antigens, CD
- Antineoplastic Agents
- Bryostatins
- Cell Cycle
- Cell Differentiation
- Cell Division
- Humans
- Lactones
- Lymphoma, B-Cell
- Macrolides
- Phenotype