Article
Human rIL4 fails to differentiate leukemic B-cell progenitors growing upon S17 stromal cell line.
Leukemia - 1 Feb 1993
Consolini R
Abstract excerpt
Stromal cells appear to be key regulatory elements in hematopoiesis and lymphopoiesis. Several stromal cell lines can support B lineage by creating a hematopoietic microenvironment via cell contact or regulatory humoral molecules. These activities have been efficiently mediated by an adipocytic stromal cell line 14F1.1 on infant leukemia cells expressing a hybrid pre-B myeloid phenotype. Several murine cell...
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