Article
Ligand-protein electrostatic interactions govern the specificity of retinol- and fatty acid-binding proteins.
Biochemistry - 26 Jan 1993
Jakoby M G, Miller K R, Toner J J, Bauman A, Cheng L, Li E, Cistola D P
Abstract excerpt
Cellular retinol-binding protein II (CRBP-II) and intestinal fatty acid-binding protein (I-FABP) are both expressed in small intestinal enterocytes and exhibit 31% sequence identity. I-FABP binds a single molecule of long-chain fatty acid and forms an ion-pair electrostatic interaction between th...
Topics
- Animals
- Arginine
- Calorimetry
- Carbon Isotopes
- Carrier Proteins
- Electricity
- Escherichia coli
- Fatty Acid-Binding Protein 7
- Fatty Acid-Binding Proteins
- Fatty Acids
- Glutamine
- Ligands
- Magnetic Resonance Spectroscopy
- Mutation
- Neoplasm Proteins
- Nerve Tissue Proteins
- Rats
- Recombinant Proteins