Article
The ovine Booroola fecundity gene (FecB) is linked to markers from a region of human chromosome 4q.
Nature genetics - 1 Aug 1993
Montgomery G W, Crawford A M, Penty J M, Dodds K G, Ede A J, Henry H M, Pierson C A, Lord E A, Galloway S M, Schmack A E
Abstract excerpt
The autosomal Booroola fecundity gene (FecB) mutation in sheep increases ovulation rate and litter size, with associated effects on ovarian physiology and hormone profiles. Analysis of segregation in twelve families (379 female progeny) identified linkage between the mutation, two microsatellite markers (OarAE101 and OarHH55, Zmax > 9.0) and epidermal growth factor (EGF) from human chromosome 4q25 (Zmax > 3.0)....
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 4
- DNA Probes
- DNA, Satellite
- Female
- Fertility
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male
- Molecular Sequence Data
- Mutation