Article
Characterization of a novel biphenotypic leukemia cell line, TA-1, with myeloperoxidase and inducible cytoplasmic mu chain: altered rearrangement patterns of antigen receptor genes.
International journal of hematology - 1 Jun 1993
Tanabe S, Fukuhara S, Yoneda T, Ohmori K, Nosaka T, Hatanaka M, Okuma M
Abstract excerpt
A novel biphenotypic cell line carrying t(9;11)(p22;q23), TA-1, was established from the peripheral blood of a patient with acute undifferentiated leukemia. The TA-1 cells simultaneously expressed lymphoid (CD19, CD20) and myeloid characteristics (CD13, CD33, myeloperoxidase) on the same cells. W...
Topics
- Acute Disease
- Adult
- Cytoplasm
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Gene Rearrangement, T-Lymphocyte
- Humans
- Immunoglobulin mu-Chains
- Leukemia
- Male
- Peroxidase
- Phenotype
- Tumor Cells, Cultured