Article
Computer-assisted identification of a putative methyltransferase domain in NS5 protein of flaviviruses and 2 protein of reovirus
1 Apr 1993
Abstract excerpt
A sequence motif that is conserved in a number of S-adenosylmethionine (SAM)-utilizing methyltransferases and is implicated in SAM binding was identified in the N-terminal portion of NS5 proteins of flaviviruses and in lambda 2 protein of reovirus. An additional conserved motif was shared by these viral proteins and two distinct groups of methyltransferases including as the prototypes Rhodobacter capsulatus...
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