Article
The probable arrangement of the helices in G protein-coupled receptors.
The EMBO journal - 1 Apr 1993
Baldwin J M
Abstract excerpt
G protein-coupled receptors form a large family of integral membrane proteins whose amino acid sequences have seven hydrophobic segments containing distinctive sequence patterns. Rhodopsin, a member of the family, is known to have transmembrane alpha-helices. The probable arrangement of the seven helices, in all receptors, was deduced from structural information extracted from a detailed analysis of the...
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