Article
Ras1-dependent signaling by ectopically-expressed Drosophila src gene product in the embryo and developing eye.
Oncogene - 1 Oct 1993
Kussick S J, Basler K, Cooper J A
Abstract excerpt
The cellular functions of the Drosophila src 64B (Dsrc) gene product, Dsrc, and of most vertebrate Src-family kinases, are unknown. We have examined the effects of over-expression of wild type and mutated forms of Dsrc in transgenic Drosophila. Expression of both wild type Dsrc and a C-terminally truncated mutant at high levels during embryonic development induced extensive tyrosine phosphorylation of cellular...
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