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Article

Spectrin alpha IIa variant in dominant and non-dominant spherocytosis.

Human genetics - 1 Sept 1993

Boivin P, Galand C, Devaux I, Lecomte M C, Garbarz M, Dhermy D

Abstract excerpt

Several polymorphic mutations are located on the spectrin alpha-chain; among these the variant termed alpha IIa is characterized by an acid shift in the isoelectric point of the tryptic digest peptides 46 kDa and 35 kDa. In this variant a single amino acid substitution (alanine to aspartic acid) occurred at position 972 of the spectrin alpha-chain due to a point mutation (GCT to GAT) in the DNA. This variant,...

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PMID: 8370581
DOI: 10.1007/BF00219683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Spectrin alpha IIa variant in dominant and non-dominant spherocytosis.PMID 8370581Read ↗

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