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Article

Amino-acid substitution in alpha-spectrin commonly coinherited with nondominant hereditary spherocytosis.

American journal of hematology - 1 Mar 1997

Tse W T, Gallagher P G, Jenkins P B, Wang Y, Benoit L, Speicher D, Winkelmann J C, Agre P, Forget B G, Marchesi S L

Abstract excerpt

Nondominant hereditary spherocytosis (ndHS) is a disorder characterized in some patients by severe hemolytic anemia and marked deficiency of erythrocyte spectrin. This report describes the identification of a variant spectrin chain, alpha-spectrin Bughill or alpha(BH), that is associated with this disorder in a number of patients. Tryptic maps of spectrin from affected individuals revealed an acidic shift in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9067503
DOI: 10.1002/(sici)1096-8652(199703)54:3<233::aid-ajh10>3.0.co;2-e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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