Article
Virulence of Salmonella typhimurium mutants for White Leghorn chicks.
Avian diseases - 1 Jan 2000
Porter S B, Tinge S A, Curtiss R
Abstract excerpt
A strain of Salmonella typhimurium that is highly virulent for 1-day-old white leghorn chicks was genetically modified by deletion (delta) of the adenylate cyclase (cya) and cyclic AMP receptor protein (crp) genes or by removal (curing) of the 91-kilobase virulence plasmid. These mutants were then compared with the wild-type S. typhimurium strain for virulence in 1-day-old chicks and for their ability to colonize...
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