Article
Chromosomal localization and regulation of the longevity determinant genes in a selected strain of Drosophila melanogaster.
Heredity - 1 Jul 1993
Buck S, Wells R A, Dudas S P, Baker G T, Arking R
Abstract excerpt
A controlled chromosome substitution experiment was performed on a strain (NDC-L) selected for long life to determine if the genes responsible for the extended-longevity phenotype could be localized to any particular chromosome(s). All 27 different possible combinations of the three major chromosomes of Drosophila melanogaster were constructed and longevities were determined on 3875 individual animals of both...
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