Article
Characterization of two allelic variants of a human pregnancy-specific glycoprotein gene.
The Journal of biological chemistry - 15 Aug 1993
Lei K J, Wang C, Chamberlin M E, Liu J L, Pan C J, Chou J Y
Abstract excerpt
The pregnancy-specific glycoproteins (PSGs) of the human placenta are a group of proteins that together with the carcinoembryonic antigens comprise a subfamily within the immunoglobulin superfamily. To study the control of PSG expression, we isolated and characterized PSG genes and identified cis-acting DNA elements in the 5'-flanking gene regions essential for PSG expression. Two overlapping PSG cosmid clones,...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- DNA
- Genetic Variation
- Glycoproteins
- Humans
- Molecular Sequence Data
- Placenta
- Pregnancy Proteins
- Pregnancy-Specific beta 1-Glycoproteins
- Promoter Regions, Genetic
- Pseudogenes
- RNA Caps
- Restriction Mapping
- Sequence Homology, Nucleic Acid
- Transcription, Genetic
