Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells.

doi:10.3109/08977199308991582

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Article

Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells.

Growth factors (Chur, Switzerland) - 1 Jan 1993

Wang E A, Israel D I, Kelly S, Luxenberg D P

Abstract excerpt

C3H10T1/2 cells are an established mesenchymal stem cell line which can differentiate into muscle, fat and cartilage cells when treated with azacytidine. Bone morphogenetic protein-2 (BMP-2) caused a dose dependent differentiation of these cells into fat, cartilage and bone cells-low concentratio...

Topics

3T3 Cells
Animals
Bone Morphogenetic Proteins
Cell Differentiation
Gene Expression
Growth Substances
Mice
Phenotype
Proteins
Stem Cells
Transfection

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