Article
Long-range surface charge-charge interactions in proteins. Comparison of experimental results with calculations from a theoretical method.
Journal of molecular biology - 20 Jul 1993
Loewenthal R, Sancho J, Reinikainen T, Fersht A R
Abstract excerpt
Long-range coulombic interaction energies between surface-charges in barnase and subtilisin have been determined to provide data for calibrating theoretical methods. The pKa of His18 in barnase can be measured accurately by titrating the fluorescence of Trp94 that is significantly quenched on pro...
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