Article
Effect of phototherapy and urocanic acid isomers on natural killer cell function.
The Journal of investigative dermatology - 1 Aug 1993
Gilmour J W, Vestey J P, George S, Norval M
Abstract excerpt
Ultraviolet (UV) radiation suppresses a variety of immune responses but it is uncertain whether this action contributes to the effectiveness of phototherapy. Urocanic acid (UCA) has been proposed as a mediator of the immunologic effects of UV. On exposure the naturally occurring trans-isomer of UCA in the skin changes into the cis-isomer, which has been demonstrated to mimic many of the immunomodulatory effects...
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