Article
The biological interaction of cis- and trans-urocanic acid and DNA.
Photodermatology, photoimmunology & photomedicine - 1 Jun 1992
Yarosh D B, Gettings S D, Alas L G, Kibitel J T, San R H, Wagner V O, McEwen G N
Abstract excerpt
The potential for the cis and trans isomers of urocanic acid to produce DNA damage was measured by assays for DNA binding (32P-postlabeling assay), for induction of DNA repair (unscheduled DNA synthesis assay) and induction of mutations (Salmonella typhimurium and Escherichia coli plate-incorporation assays). These assays did not detect any evidence of a direct effect of either isomer of urocanic acid on DNA over...
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