Article
The biological interaction of cis- and trans-urocanic acid and DNA.
Photodermatology, photoimmunology & photomedicine - 1 Jun 1992
Yarosh D B, Gettings S D, Alas L G, Kibitel J T, San R H, Wagner V O, McEwen G N
Abstract excerpt
The potential for the cis and trans isomers of urocanic acid to produce DNA damage was measured by assays for DNA binding (32P-postlabeling assay), for induction of DNA repair (unscheduled DNA synthesis assay) and induction of mutations (Salmonella typhimurium and Escherichia coli plate-incorpora...
Topics
- Animals
- Cattle
- Cell Line, Transformed
- DNA
- DNA Damage
- DNA Repair
- DNA, Bacterial
- Escherichia coli
- Fibroblasts
- Humans
- Male
- Microsomes, Liver
- Mutation
- Phosphorus Radioisotopes
- Rats
- Rats, Sprague-Dawley
- Salmonella typhimurium
- Stereoisomerism
