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Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.

Molecular biology and evolution - 1 May 1993

Tamura K, Nei M

Abstract excerpt

Examining the pattern of nucleotide substitution for the control region of mitochondrial DNA (mtDNA) in humans and chimpanzees, we developed a new mathematical method for estimating the number of transitional and transversional substitutions per site, as well as the total number of nucleotide substitutions. In this method, excess transitions, unequal nucleotide frequencies, and variation of substitution rate...

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PMID: 8336541
DOI: 10.1093/oxfordjournals.molbev.a040023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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