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Article

Phenotypic and genotypic variation in Giardia lamblia isolates during chronic infection.

Gut - 1 Jan 1994

Butcher P D, Cevallos A M, Carnaby S, Alstead E M, Swarbrick E T, Farthing M J

Abstract excerpt

Two Giardia isolates were axenised in vitro after recovery by duodenal aspiration from a man with hypo-gamma globulinaemia and chronic giardiasis, before and after three unsuccessful courses of metronidazole. In vitro drug sensitivity assays showed that the pretreatment isolate was sensitive to metronidazole with minimum inhibitory concentration (MIC) and dose that inhibited growth by 50% (ED50) values of 0.1 and...

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Identifiers

PMID: 8307449
DOI: 10.1136/gut.35.1.51
PMCID: PMC1374631

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