Article
Selection of specific genotypes of Giardia intestinalis by growth in vitro and in vivo.
Parasitology - 1 Dec 1992
Andrews R H, Chilton N B, Mayrhofer G
Abstract excerpt
This study examined whether allelic changes observed when clinical isolates of Giardia intestinalis made in suckling mice were adapted to in vitro growth occurred as a result of gene switching (alternate isoenzymes) or through selection of organisms with different genotypes from mixed infections. Samples were compared electrophoretically at 20 enzyme loci. Marked allelic differences were detected between the...
Topics
- Alleles
- Animals
- Animals, Suckling
- Enzymes
- Gene Expression Regulation
- Genes, Protozoan
- Genes, Switch
- Genetic Variation
- Genotype
- Giardia
- Giardiasis
- Mice
