Article
Transmembrane helix-helix interactions in F0 suggested by suppressor mutations to Ala24-->Asp/Asp61-->Gly mutant of ATP synthase subunit.
The Journal of biological chemistry - 28 Jan 1994
Fraga D, Hermolin J, Fillingame R H
Abstract excerpt
A mutant of ATP synthase subunit c was isolated in which the essential aspartate was exchanged from position 61 on transmembrane helix-2 to position 24 on transmembrane helix-1 (Miller, M. J., Oldenburg, M., and Fillingame, R. H. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 4900-4904). The H+ trans...
Topics
- Alanine
- Amino Acid Sequence
- Aspartic Acid
- Cell Membrane
- Chromosomes, Bacterial
- DNA, Bacterial
- Escherichia coli
- Genetic Variation
- Glycine
- Kinetics
- Macromolecular Substances
- Models, Structural
- Point Mutation
- Protein Structure, Secondary
- Proton-Translocating ATPases