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Article

Molecular genetics of cryptopleurine resistance in Saccharomyces cerevisiae: expression of a ribosomal protein gene family.

Genetics - 1 Nov 1993

Paulovich A G, Thompson J R, Larkin J C, Li Z, Woolford J L

Abstract excerpt

The Saccharomyces cerevisiae CRY1 gene encodes the 40S ribosomal subunit protein rp59 and confers sensitivity to the protein synthesis inhibitor cryptopleurine. A yeast strain containing the cry1-delta 1::URA3 null allele is viable, cryptopleurine sensitive (CryS), and expresses rp59 mRNA, sugges...

Topics

Alkaloids
Alleles
Amino Acid Sequence
Base Sequence
Chromosome Mapping
DNA Primers
DNA, Fungal
Drug Resistance, Microbial
Gene Expression
Genes, Fungal
Molecular Sequence Data
Multigene Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Protein Synthesis Inhibitors

Ribosomal Proteins

Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8293976
DOI: 10.1093/genetics/135.3.719
PMCID: PMC1205715

Genes

CRY2
CRY1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8293976-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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