A cytolysin encoded by Salmonella is required for survival within macrophages.

doi:10.1073/pnas.91.2.489

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Article

A cytolysin encoded by Salmonella is required for survival within macrophages.

Proceedings of the National Academy of Sciences of the United States of America - 18 Jan 1994

Libby S J, Goebel W, Ludwig A, Buchmeier N, Bowe F, Fang F C, Guiney D G, Songer J G, Heffron F

Abstract excerpt

A Salmonella gene encoding a cytolysin has been identified by screening for hemolysis on blood agar. DNA sequence analyses together with genetic mapping in Salmonella suggest that it is unrelated to other toxins or hemolysins. The gene (slyA) is present in every strain of Salmonella examined, in...

Topics

Amino Acid Sequence
Animals
Bacterial Proteins
Bacterial Toxins
Base Sequence
Chromosome Mapping
Cloning, Molecular
Cytotoxins
DNA, Bacterial
Genes, Bacterial
Hemolysin Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macrophages, Peritoneal

Mice

Molecular Sequence Data

Mutation

Salmonella Infections, Animal

Salmonella typhimurium

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 8290552
DOI: 10.1073/pnas.91.2.489
PMCID: PMC42974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8290552-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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