Article
Polymorphism and selection of rpoS in pathogenic Escherichia coli.
BMC microbiology - 3 Jun 2009
Dong Tao, Chiang Sarah M, Joyce Charlie, Yu Rosemary, Schellhorn Herb E
Abstract excerpt
BACKGROUND: Though RpoS is important for survival of pathogenic Escherichia coli in natural environments, polymorphism in the rpoS gene is common. However, the causes of this polymorphism and consequential physiological effects on gene expression in pathogenic strains are not fully understood. RESULTS: In this study, we found that growth on non-preferred carbon sources can efficiently select for loss of RpoS in...
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