Paracrine and autocrine growth mechanisms in tumor metastasis to specific sites with particular emphasis on brain and lung metastasis.

doi:10.1007/BF00665961

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Article

Paracrine and autocrine growth mechanisms in tumor metastasis to specific sites with particular emphasis on brain and lung metastasis.

Cancer metastasis reviews - 1 Sept 1993

Nicolson G L

Abstract excerpt

Once metastatic cells successfully seed at distant sites, their clinical detection and danger to the host are dependent on growth to form gross metastases. Metastatic tumor cells proliferate in response to local paracrine growth factors and inhibitors, and their growth also depends on production...

Topics

Animals
Brain Neoplasms
Cell Division
Hormones
Humans
Lung Neoplasms
Neoplasm Metastasis
Phenotype
Transferrin

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