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Article

Defective receptors for platelet-derived growth factor AA in human fibroblasts with mutant insulin receptors.

Biochemical and biophysical research communications - 15 Dec 1993

Longo N

Abstract excerpt

Leprechaunism is an inherited disorder characterized by growth restriction and severe insulin resistance and caused by mutations in the insulin receptor gene. Cells from these patients have defective insulin binding. Fibroblasts from some patients have concomitant defects in other tyrosine kinase receptors, such as those for Insulin-like Growth Factor I (IGF-I) and Epidermal Growth Factor (EGF). In this report,...

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Identifiers

PMID: 8267620
DOI: 10.1006/bbrc.1993.2551

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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