Evidence for a gene cluster involving trichothecene-pathway biosynthetic genes in Fusarium sporotrichioides.

doi:10.1007/BF00336778

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Article

Evidence for a gene cluster involving trichothecene-pathway biosynthetic genes in Fusarium sporotrichioides.

Current genetics - 1 Oct 1993

Hohn T M, McCormick S P, Desjardins A E

Abstract excerpt

Two overlapping cosmid clones (Cos1-1 and Cos9-1) carrying the Tox5 gene were isolated from a library of F. sporotrichioides strain NRRL 3299 genomic DNA. These cosmids were used to transform three T-2 toxin-deficient mutants that are blocked at different steps in the trichothecene pathway. Both...

Topics

Cloning, Molecular
Fusarium
Genes, Fungal
Genetic Complementation Test
Multigene Family
Mutation
Restriction Mapping
T-2 Toxin
Transformation, Genetic
Trichothecenes

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