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Article

The Tri4 gene of Fusarium sporotrichioides encodes a cytochrome P450 monooxygenase involved in trichothecene biosynthesis.

Molecular & general genetics : MGG - 22 Jul 1995

Hohn T M, Desjardins A E, McCormick S P

Abstract excerpt

The Tri4 gene of Fusarium sporotrichioides was isolated from a cloned DNA fragment carrying the Tri5 gene by complementation of a Tri4- mutant. The nucleotide sequence of Tri4 was determined and the locations of three introns were identified. Analysis of Tri4 mRNA levels revealed that transcription reached maximum levels coincidently with the onset of trichothecene biosynthesis, and then declined 20-fold over the...

Topics

Amino Acid Sequence
Base Sequence
Cytochrome P-450 Enzyme System
DNA, Fungal
Fusarium
Genes, Fungal
Molecular Sequence Data
Mutation
Oxygenases
Protein Conformation
Sequence Homology, Amino Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

Trichothecenes

Source

Identifiers

PMID: 7651333
DOI: 10.1007/BF02456618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7651333-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The Tri4 gene of Fusarium sporotrichioides encodes a cytochrome P450 monooxygenase involved in trichothecene biosynthesis.PMID 7651333Read ↗

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