Evidence of a major gene with pleiotropic action for a cardiovascular disease risk syndrome in children younger than 14 years.

Abstract excerpt

OBJECTIVE: To test the plausibility of the existence of a genetically based syndrome involving obesity, hypertension, and a central deposition of body fat. DESIGN: Survey of a random stratified sample of the US population. PARTICIPANTS: Male and female children aged 13 years or younger (mean, 5.3 years; SD, 3.7 years; median, 4.0 years; range, 6 months to 13 years) were chosen from National Health and Nutrition...

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