Primary structure and muscle-specific expression of the 50-kDa dystrophin-associated glycoprotein (adhalin).

Abstract excerpt

The 50-kDa dystrophin-associated glycoprotein (50-DAG) is a component of the dystrophin-glycoprotein complex, which links the muscle cytoskeleton to the extracellular matrix. 50-DAG is specifically deficient in skeletal muscle of patients with severe childhood autosomal recessive muscular dystrophy and in skeletal and cardiac muscles of BIO 14.6 cardiomyopathic hamsters. The lack of 50-DAG leads to a disruption...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biotin and Related Studies
• Share to Cardiomyopathy and Myosin Studies
• Share to Muscle Physiology and Disorders