Article
Thyroid hormone transport proteins.
Clinics in laboratory medicine - 1 Sept 1993
Bartalena L, Robbins J
Abstract excerpt
TBG, TTR, and albumin are quantitatively the most important thyroid hormone binding proteins in humans. Only a minute fraction of T3 and T4 circulates unbound, but it is this free hormone that is metabolically active at the tissue level, and, therefore, responsible for thyroid status. Inherited or acquired variations in the concentration or affinity of these proteins may produce substantial changes in serum total...
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