Dysprealbuminemic hyperthyroxinemia in a patient with hyperthyroid graves disease.

Abstract excerpt

Rare mutant forms of circulating albumin and prealbumin [transthyretin (TTR)] have increased binding affinity for thyroxine (T4). Patients with these variant plasma proteins, as a result of inherited mutations or as a paraneoplastic phenomenon, typically present with increased serum total T4 and, by some assay methodologies, an increased free T4 as well. Although these individuals are, in fact, euthyroid,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diagnosis, Differential
• Share to Graves Disease
• Share to Hypothyroidism