Article
The lower level of natural anti-Thomsen-Friedenreich antigen (TFA) agglutinins in sera of patients with gastric cancer related to ABO(H) blood-group phenotype.
International journal of cancer - 16 Mar 1995
Kurtenkov O, Klaamas K, Miljukhina L
Abstract excerpt
The TFA is a tumor-associated, blood-group-related glycosidic precursor structure [Gal(beta 1-3)GalNAc]. Its expression in carcinomas is accompanied by a decrease of natural TFA antibodies in serum. The relationship between the ABO(H)-blood-group phenotype and natural anti-TFA immune response in patients with gastric cancer was studied. The level of TFA agglutinins in the sera of patients with gastric cancer and...
Topics
- ABO Blood-Group System
- Aged
- Agglutinins
- Antibodies
- Case-Control Studies
- Female
- Humans
- Male
- Middle Aged
- Phenotype
- Stomach Neoplasms
